Pharmacy Times – May 2017

 

Drug Interactions: Insights and Observations

 

Using Grapefruit to Improve Drug Response

John R. Horn, PharmD, FCCP and Philip D. Hansten, PharmD

 

 

References.

1. Bailey DG, Spence JD, Edgar B, Bayliff CD, Arnold JM. Ethanol enhances the hemodynamic effects of felodipine. Clin Invest Med. 19898;12:357-362.

2. Tsuji H, Ohmura K Nakashima R, Hashimoto, M, Imura, Y, Yukawa N, Yoshifuji H, Fujii T, Mimori T. Efficacy and safety of grapefruit juice intake accompanying tacrolimus treatment in connective tissue disease patients. Intern Med. 2016;55:1547-1552.

3. Lee JW, Morris JK, Wald NJ. Grapefruit juice and statins. Am J Med. 2016;129:26-29.

4. Bailey DG. Predicting clinical relevance of grapefruit-drug interactions: a complicated process. J Clin Pharm Ther. 2017;42:125-127.