Drug Interactions: Insights and Observations

 

Disaster: Failing to Consider

the Time Course of Drug Interactions

 

John R. Horn, PharmD, FCCP, and Philip Hansten, PharmD

 

 

References:

 

1. Allison EJ Jr, et al. Spinal epidural haematoma as a result of warfarin/fluconazole drug interaction. Eur J Emerg Med. 2002;9:175-7.

 

2. Black DJ, et al. Warfarin-fluconazole. II. A metabolically based drug interaction: in vivo studies. Drug Metab Dispos. 1996 Apr;24(4):422-8.