Pharmacy Times – August 2014


Drug Interactions: Insights and Observations


Interactions with Hepatitis C Antivirals




John R. Horn, PharmD, FCCP and Philip D. Hansten, PharmD



1. Wilby KJ et al. A review of drug interactions with boceprevir and telaprevir: implications for HIV and transplant patients. Ann Hepatol. 2012;11:179-85.

2. Victrelis. [package insert]. Whitehorse Station, NJ, Merck Sharp & Dohme Corp., 2013.

3. Lee JE et al. Effect of the hepatitis C virus protease inhibitor telaprevir on the pharmacokinetics of amlodipine and atorvastatin. Antimicrob Agents Chemother. 2011;55:4569-74.

4. Olysio [package insert]. Foster City, CA, Gilead Sciences, Inc., 2013

5. Sovaldi [package insert]. Titusville, NJ, Janssen Products, LP., 2013.