Pharmacy Times – March 2017
Drug Interactions: Insights and Observations
Adverse Outcomes in Stabilized Patients
John R. Horn, PharmD, FCCP and Philip D. Hansten, PharmD
1. Patel S, Andres J, Qureshi K. An unexpected interation between sofosbuvir/ledipasvir and atorvastatin and colchicine causing rhabdomyolysis in a patient with impaired renal function. Case Rep Med. 2016;2016:3191089.
2. Davis MW, Wason S. Effect of steady-state atorvastatin on the pharmacokinetics of a single dose of colchicine in healthy adults under fasted conditions. Clin Drug Investig. 2014;34:259-267.