John R. Horn, PharmD, FCCP and Philip D. Hansten, PharmD
References
1. Wagner DJ, Hu
T, Wang J. Polyspecific organic cation transporters
and their impact on drug intracellular levels and pharmacodynamics. Pharmacol Res. 2016;111:237-46.
Doi:10.1016/j.phrs.2016.06.002.
2. Cho SK, Kim CO,
Park ES et al. Verapamil decreases the glucose-lowering effect of metformin in
healthy volunteers. Br J Clin Pharmacol.
2014;78:1426-32. Doi:
10.1111/pcp.12476.
3. Ahlin G, Chen L, Lazorova L, et
al. Genotype-dependent effects of inhibitors of the organic cation transporter,
OCT1: predictions of metformin interactions. Pharmacogenomics J. 2011;11:400-11. Doi. 10.1038/tpj.2010.54.
4. Cho SK, Yoon
JS, Lee MG et al. Rifampin enhances the glucose-lowering effect of metformin
and increases OCT1 mRNA levels in healthy participants. Clin Pharmacol Ther. 2011;89:416-21. Doi.:10.1038/cpt.2010.266.