Pharmacy Times – December 2010

Drug Interactions: Insights and Observations

Dabigatran: A New Oral Anticoagulant with New Interactions

John R. Horn, PharmD, FCCP and Philip D. Hansten, PharmD


1. Pradaxa. [package insert]. Ridgefield CT; Boehringer Ingelheim Pharmaceuticals, Inc, 2010.

2. Stangier J et al. Pharmacokinetics and pharmacodynamics of the direct oral thrombin inhibitor dabigatran in healthy elderly subjects. Clin Pharmacokinet. 2008;47:47-59.

3. FDA briefing information, dabigatran etexilate mesylate capsules for September 20, 2010 meeting of the cardiovascular and renal drugs advisory committee.