Avoiding Lapatinib Interactions
November
2012
John R. Horn, PharmD, FCCP, and Philip D. Hansten, PharmD
References:
1. Teo
YL et al. Efffect of CYP3A4 inducer dexamethasone on
hepatotoxicity of lapatinib: clinical and in vitro evidence. Breast Cancer Res
Treat. 2012;133:703-711.
2. Smith DA et al. Effects
of ketoconazole and carbamazepine on lapatinib pharmacokinetics in healthy
subjects. Br J Clin Pharmacol. 2009;67:421-426.