Pharmacy Times October 2006


Drug Interactions: Insights and Observations


Predicting the Magnitude of Drug Interactions: The Final Frontier


John R. Horn, PharmD, FCCP and Philip D. Hansten, PharmD




  1. Horn JR, Hansten PD. The Importance of the Order of Drug Administration. Pharmacy Times. 2005;71(February):96.
  2. Horn JR, Hansten PD. Genetics and Drug Interactions: Understanding an Important Variable in Patient Response. Pharmacy Times. 2006;in press.
  3. Kantola T et al. Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin acid. Clin Pharmacol Ther.1998;63:397-402.
  4. Rogers JD et al. Grapefruit juice has minimal effects on plasma concentrations of lovastatin-derived 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. Clin Pharmacol Ther. 1999;66:358-66.