Drug Interactions: Insights and Observations


John R. Horn, PharmD, FCCP and Philip D. Hansten, PharmD


Cholinergic – Anticholinergic: Drug Interactions





  1. 1.     Tune L, Carr S et al. Anticholinergic effects of drugs commonly prescribed for the elderly: potential means for assessing risk of delirium. Am J Psychiatry. 1992;149:1393-4.
    1. 2.     Lu C-J and Tune L. Chronic exposure to anticholinergic medications adversely affects the course of alzheimer disease. Am J Geriatr Psychiatry. 2003;11:458-60.
      1. 3.     Carnahan RM, Lund BC et al. The concurrent use of anticholinergics and cholinesterase inhibitors: rare event or common practice? J Am Geriatr Soc.2004;52:2082-7.
        1. 4.     Roe CM, Anderson MJ et al. Use of anticholinergic medications by older adults with dementia. J Am Geriatr Soc. 2002;50:836-42.
          1. 5.     Mulsant BH, Gharabawi GM et al. Correlates of anticholinergic activity in patients with dementia and psychosis treated with risperidone or olanzapine. J Clin Psychiatry.2004;65:1708-14.