Pharmacy Times – April 2008
Drug Interactions: Insights and Observations
Clopidogrel: Interactions May Lead to Loss of Antiplatelet Activity
John R. Horn, PharmD,
FCCP and Philip D. Hansten, PharmD
- Gilard M et al. Influence of
omeprazole on the antiplatelet action of clopidogrel associated to
aspirin. J Thromb Haemost. 2006;4:2508.
- Gilard M et al. Influecne of
omeprazole on the antiplatelet action of clopidogrel associated with
aspirin. J Am Col Card. 2008;51:256.
- Matetzky S et al. Clopidogrel
resistance is associated with increased risk of recurrent atherothrombotic
events in patients with acute myocardial infarction. Circulation.